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Diagnostic Accuracy of Biopsy Urease Test in Diagnosis of Gastritis Among Patients Attending Gastroenterology Units in Khartoum State

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dc.contributor.author Musa, Mohanad Altahir Ismail
dc.contributor.author Supervisor,- Wafa Ibrahim Elhag
dc.date.accessioned 2015-02-23T08:57:21Z
dc.date.available 2015-02-23T08:57:21Z
dc.date.issued 2014-08-27
dc.identifier.citation Musa,Mohanad Altahir Ismail.Diagnostic Accuracy of Biopsy Urease Test in Diagnosis of Gastritis Among Patients Attending Gastroenterology Units in Khartoum State/Mohanad Altahir Ismail Musa;Wafa Ibrahim Elhag.-Khartoum:Sudan University of Science & Technology,Medical Laboratory Science,2014.-54p.:ill.;28cm.-M.Sc. en_US
dc.identifier.uri http://repository.sustech.edu/handle/123456789/10658
dc.description Thesis en_US
dc.description.abstract Recently Helicobacter pylori (H. pylori) has been involved in many serious diseases such as peptic ulcer and ended with gastric cancer, which can be prevented using specific diagnostic test and treatment. This study evaluated the diagnostic accuracy of urease test in the diagnosis of Helicobacter pylori (H. pylori) in patients with gastritis. Fifty consecutive adult patients with gastritis presenting for endoscopy were recruited after giving informed consent. Two gastric biopsies were collected at endoscopy unit for Urease test and Polymerase Chain Reaction (PCR). Sensitivity, specificity, of urease test was calculated using PCR as reference standard. Of the 50 subjects, there were 25 (50%) positive by urease test, 26 (52%) positive by PCR (polymerase chain reaction). And 25 (50%) negative by urease, 24 (48%) negative by PCR. The sensitivity, specificity, of urease test were 84.6% and 87.5% respectively. Statisitical analysis showed no relation between gender, age or symptoms with H.pylori 16S rRNA gene detection Compared with PCR, urease test is simpler, it gives more rapid test result and it is much cheaper. Practically overcomes these drawbacks since it is not dependent on the experience and accuracy of individual laboratories as in the case of other biopsy based methods. en_US
dc.description.sponsorship Sudan University of Science and Technology en_US
dc.language.iso en en_US
dc.publisher Sudan University of Science & Technology en_US
dc.subject Accuracy-Biopsy Urease en_US
dc.subject Gastritis en_US
dc.subject Gastroenterology-Khartoum State en_US
dc.title Diagnostic Accuracy of Biopsy Urease Test in Diagnosis of Gastritis Among Patients Attending Gastroenterology Units in Khartoum State en_US
dc.title.alternative الحساسيه والنوعيه التشخيصيه لاختبار اليورياز لتشخيص التهاب المعده للمرضى فى وحدات مبحث المعده والامعاء بولايه الخرطوم en_US
dc.type Thesis en_US


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