Abstract:
Plasma
fibrinogen,
total
cholesterol
triglycerides,
TroponinT and cardiac enzymes were measured in control and
53 patients admitted CCU at Elain Governmental Hospital
(MAE) suffering acute chest pain and suspected as having
myocardial infarction. The patients admitted the hospital at
.varying times of chest pain attack
The results obtained from this study revealed that 67% of
patients admitted the CCU of Elain Hospital were diagnosed as
ECG positive, and 58% were elderly. The study also showed
that 38% the chest pain patients were hypertensive, and 55%
were diabetics. It also pointed out that the chest pain attack was
at early morning in about 63%, and 37% of patents had the
attack during the evening and most of them presented with
severe stress and physical and emotional conditions. The study
also demonstrated that about 46% of chest pain patients were
heavily smokers, and the majority of them 72% did not claimed
family history of MI disease, and 77% of then claimed that no
incidence of sudden death in their families were occurred.
.Obesity was found in about 69% of the chest pain patients
Fibrinogen concentration in control as well as chest pain
patients were measured as soon CCU, admission after 10 – 12
hours following the chest pain attack and after 24 hours of chest
pain attack. Three levels of plasma fibrinogen concentration
were obtained, high value, e.g. about 5.85 g/dL were found after
6 hours of chest pain attack in about 46% of patents, borderline
value e.g. 3.43 g/L in about 30% of the patients, and lower value
e.g. 2.24 g/L in about 24% of patients theses levels were
persisted up to 24 hours of CCU admission before it then start to
decline after 24 hours to give values of 4.37 g/L as high value in
about 11% of patients, 2.87 g/L as middle value in about 56% of
the patients, and 1.72 g/L in as low value in about 33% of
.patients
It noticeable that the increase in plasma fibrinogen was
.correlated with increased plasma viscosity
Total cholesterol and triglycerides were also found to
elevated to a significant level when compared with control in
chest pain patients. Triglycerides were highly elevated than total
.cholesterol
The activity of all cardiac enzymes (LDH, AST, CK, CK-
MB) and tropaninT were significantly raised in which CK-M,
.CK, and TroponinT were more elevated