Abstract:
This is a prospective study conducted during the period May
2005 to January2006 to determine type of jaundice in adult
sudanaces patients with cancer by estimating the liver function and
serological of hepatitis B&C Virus.
The population studied include patient with different types of
cancer, and having jaundice who had attended the Radiation and
isotope center Khartoum (RICK) also from Ibn sina hospital.
Samples from 50 patients from different types of cancer including
oesophagus comprised 1%, stomach cancer comprised 1%, breast
comprised 1%, rectum comprised 1%, cervix comprised 1%, non
Hodgkin, s lymphoma comprised 2%, lymphoma comprised 1%,
gallbladder comprised 6%, leukemia comprised 9%, pancreas
comprised 10%, the primary hepatocellular carcinoma comprised 6%, and
metastatsis to liver comprised 14%, and, from 50 apparently healthy
individuals as control had taken, then the total plasma protein
concentration mean 14.2g/dl, albumin concentration mean 7.0g/dl,
globulin concentration mean 701g/dl, total bilirubin concentration
mean 9.7mg/dl , direct bilirubin concentration mean 5.7mg/dl,
indirect bilirubin concentration mean 4.1mg/dl, enzyme ALP
concentration mean 325.6u/l, GPT concentration mean100.1u/l ,
GOT concentration mean 70.2u/l, γ-GT concentration mean
60.3u/l,and surgical hepatitis B&C virus were estimated in order
determine the cause of jaundice is it due to the primary tumor,
metastatasis or blood transfusion or due to complication of treatment
either chemotherapy or radiotherapy.