Abstract:
This study had been conducted to determine the susceptibility of
Methicillin-Resistant
Staphylococcus
aureus
(MRSA)
and
staphylococcus aureus to selected antibiotics traditionally used in Sudan
such as vancomycin, erythromycin, ciprofloxacin and gentamicin.
Conventional techniques were used to isolate and identify S.
aureus and MRSA strains. NCCLS modified-Kirby-Bauer disc diffusion
technique had been used to carry out the susceptibility testing.
A total of one hundred strains of S. aureus were isolated from the
clinical specimens 36.6% from infected wound, 94.1% from ear infection
and 59.1% from UTI patients. Only 21% of S. aureus isolates were
MRSA.
The resistance rate of oxacillin (represent methicillin),
gentamicin, erythromycin and ciprofloxacin against S. aureus strains
were 21%, 22%, 14% and 4% respectively.
The resistance rate of oxacillin, gentamicin, erythromycin and
ciprofloxacin against MRSA were 100%, 90.5%, 33.3% and 19.05 %
respectively. All the MRSA strains were sensitive to vancomycin.