Abstract:
The prevalence of type 2 DM has been increasing significantly in all countries
during the last century. It is widely recognized that the most serious problem in
DM arises from the insidiously developing vascular complications.
This is a cross-sectional study, aimed to determine the level of serum
phospholipids in Sudanese patients suffering from diabetes mellitus type 2, during
the period of April 2010-july 2010. Fifty samples were collected from Almotkamil
centre. The study included both sexes, 25 males aged (45-70years), whereas, 25
were females aged (45-68years).
2.5 mls of venous blood were taken from each patient in lithium heparin
container, serum was obtained in plain container, and the samples were analyzed
for serum phospholipids levels using spectrophotometer.
Statistical analysis of the results showed that, the means of serum phospholipids
in diabetic patients was higher( 275.82 mg/dl, p. value 0.000) compared to the
reference value of phospholipids levels.
From the result of the present study, it is concluded that; the plasma
phospholipids levels represent a marker for accelerated atherosclerosis, particularly
in type 2 diabetic patients. Thus, measurement of plasma phospholipids could be
useful for the stratification of cardiovascular risk.