Abstract:
This study was conducted during the period from April to
August 2013 to determine the seroprevalence of human
cytomegalovirus (HCMV) among renal transplant recipients
. at East Nile Model Hospital
A total of 120 patients were included in this study. One
hundred (n=100) subjects were renal transplant recipients
attending the clinics of East Nile Model Hospital for clinics
care, the remaining twenty (n=20) subject were apparently
healthy, non of the renal transplant recipients with no history
of renal transplant included as control group. The ages of all
.the patients ranged from 20-60 years
Personal and clinical data were collected by questionnaire
after a verbal consent, serum samples were collected, tested
for CMV IgG and IgM using enzyme-linked immunosorbent
.(assay (ELISA
Out of the 100 renal transplant recipients tested 90\100
(90%) and out of control group tested 19\20 (95%) were
positive for CMV IgG. While Out of the 100 renal transplant
recipients tested only 2\100 (2%) and out of the control
group tested 1\20(5%) were positive for CMV IgM. The age,
and distribution among male and female were significantly
associated (p< 0.05) with CMV IgG\IgM seropositivity. While
the educational level were not significantly (p> 0.05)
.associated with CMV infection
5The results revealed that the IgG and IgM of HCMV increased
with ages. Also the results showed that the incidence of CMV
.((IgG, IgM) was significantly increased in males (P< 0.05